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The science behind Boone

How Boone connects your biology and your diet

Two layers of evidence, analysed separately and then brought together: selected genetic variants linked to how your body handles nutrients, and a detailed picture of what you actually eat over time.

Your biologySelected genetic variantsLipid metabolismGlucose responseCaffeineVitamin use
Your dietWhat you actually eatMacronutrients29 micronutrientsProcessingPatterns over time
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Context for your choicesHow your everyday diet lines up with your biology, over weeks and months.
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Evidence-gradedOnly genetic variants with credible, published scientific support are used.
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Patterns, not single mealsDiet is analysed over weeks and months, not judged meal by meal.
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Context, not diagnosisBoone does not diagnose disease or make deterministic health predictions.
Part 1

Understanding your biology

It starts with a small saliva sample. The aim is not to diagnose disease or make medical predictions, but to understand natural genetic variation that can influence how the body interacts with nutrients.

1

Genomic analysis

Saliva samples are processed by accredited genomic laboratories using widely used genotyping technology. This reads thousands of locations across the genome, including small natural differences in DNA called single nucleotide polymorphisms (SNPs).

Accredited labsGenotypingSNPs
2

Selecting diet-relevant variants

Not all genetic variants are relevant to nutrition. Boone focuses on a selected subset that published nutrigenetics research has linked to how the body processes fats, carbohydrates, caffeine and certain vitamins.

NutrigeneticsPublished research
3

Interpreting genetic traits

Variants rarely act alone, so related variants are considered together to give insight into broader traits that may influence how certain nutrients interact with your body.

Lipid metabolismGlucose responseCaffeine metabolismVitamin utilisation
How we choose variants

Not every variant makes the cut

From the full genomic dataset, Boone focuses on a selected subset of variants linked to diet-related processes in published nutrigenetics research, graded with evidence frameworks so only those with credible scientific support are used.

We prioritise
1Replicated findings
2Intervention studies
3Larger study populations
4Strong statistical significance
5Meaningful effect sizes
Part 2

Analysing your diet

Boone converts meals into structured nutrition data and looks at three complementary aspects, each giving a different view of dietary patterns and quality.

Energy

Macronutrients

Carbohydrates, fats and protein provide energy and support metabolism and tissue maintenance. Their balance can influence how the body regulates energy and blood glucose.

Boone estimates macronutrients for every meal and tracks how your energy sources are distributed over time.

Vitamins and minerals

Micronutrients

Nutrients such as iron, magnesium, vitamin D, vitamin B12 and folate support functions from energy metabolism and immunity to bone health. Intake varies day to day, so patterns matter.

Boone tracks 29 vitamins and minerals against reference values to highlight possible gaps.

Food quality

Food processing

Research in nutritional epidemiology has increasingly linked high consumption of ultra-processed foods with poorer long-term health outcomes, including obesity and metabolic disease.

Boone rates the level of processing in what you eat, so you can see what share of your diet is ultra-processed.

UEA
Our researchOur processing ratings build on our own research with the University of East AngliaRead the preprint on SSRN →
Part 3

Connecting diet and biology

Understanding biology and diet separately is only part of the picture. By analysing meals over time, Boone finds patterns in nutrient intake, dietary balance and processing, then views them alongside traits derived from your genetic variation.

That puts your everyday eating in a biological context, so you can see how your diet may support or interact with your underlying physiology.

An honest note

Genetic effects in nutrition are typically modest.

Lifestyle, environment and long-term habits remain critical drivers of health. That's why Boone presents genetics as context for understanding your diet over time, not as deterministic predictions about health.

Personalised nutrition, powered by your biology.

Start with the app for free, or add a DNA test for the full picture.