Sprite uses Acesulfame K (E950) and Sucralose (E955) in place of some of the sugar. A single can (330ml) contains 86 kcal and 20.8g of sugar.
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Sprite contains 26 kcal, 6.4g of carbohydrate (6.3g sugar) per 100ml.
Sprite contains no fruit juice — the lemon and lime flavour comes entirely from natural flavourings rather than juice content. At 6.3g of sugar per 100ml it sits in the lower Sugar Tax band and partially uses sweeteners alongside sugar. Sprite is the UK's most-consumed flavoured carbonated soft drink that isn't cola, with approximately 5.6 million regular consumers in 2023.
Sprite contains 6.3g of sugar per 100ml, placing it in the lower levy band under the Soft Drinks Industry Levy. A single can (330ml) delivers 20.8g of sugar, 69% of the adult daily free sugar limit.
Sprite uses Acesulfame K (E950) and Sucralose (E955) in place of some of the sugar, with multiple sweeteners blended to better replicate the taste of sugar than any single sweetener can alone. Sweeteners deliver a sweet taste without the calories of sugar, but they are not nutritionally neutral — the evidence on their effects is more nuanced than most drinks marketing acknowledges.
In 2023 the World Health Organization issued a formal advisory recommending against using non-sugar sweeteners for weight control, stating that the long-term evidence does not show they help people manage weight or reduce the risk of obesity-related conditions. The WHO classified its guidance as a conditional recommendation, reflecting that the evidence is still emerging, but the direction is clear: sweeteners are not a straightforward healthy alternative to sugar.
A growing body of research suggests artificial sweeteners may disrupt the gut microbiome, the community of bacteria in the digestive tract that plays a role in metabolism, immunity and mood regulation. A 2022 study published in Cell found that sucralose, saccharin and stevia altered gut bacterial composition in healthy adults, with individual responses varying significantly. The long-term significance of these microbiome changes is not yet established, but the findings support treating sweeteners as active food compounds rather than inert additives.
Sweeteners may also affect appetite regulation. Because they stimulate sweet taste receptors without delivering the expected calories, some research suggests the brain's reward response to sweet taste becomes partially decoupled from energy intake over time. The evidence here is contested: some studies find sweetener users compensate by eating more elsewhere, while others find no effect. What is clear is that sweetened drinks, whether sugar-sweetened or sweetener-sweetened, are associated in epidemiological data with continued desire for sweet-tasting foods rather than reducing it.
Sucralose is derived from sugar through a chemical process that substitutes three hydroxyl groups with chlorine atoms. Unlike aspartame, it is heat-stable and passes through the body largely unchanged. Some in vitro research has raised questions about whether sucralose degrades into potentially harmful compounds at high temperatures, but the European Food Safety Authority reviewed these studies and concluded that sucralose at normal dietary exposure levels is safe. The 2022 Cell study specifically identified sucralose as one of the sweeteners that most significantly altered gut microbiome composition in human subjects.
None of this means sweetener-containing drinks are dangerous at normal levels of consumption. Regulatory agencies in the UK, EU and worldwide continue to approve sweeteners at current dietary intake levels. The more useful question for daily nutrition decisions is whether drinks using sweeteners are genuinely better than the alternatives. The honest answer: a sweetener-containing drink is likely lower in calories and sugar than the full-sugar equivalent, but is probably not as neutral as drinking water, and should not be treated as a free pass to unlimited consumption.
Nutrition information from official brand UK nutrition panels, Coca-Cola GB nutrition pages, UK retailer product listings, and independent nutritionist analyses. Figures per 100ml; per-serving values are proportional estimates. Sugar Tax (SDIL) status based on UK sugar content thresholds at time of writing — brands may reformulate. Caffeine figures from EU/UK mandatory nutrition labelling. Reference intakes: EU Reference Intakes for an average adult (2,000 kcal). Fruit juice is subject to the SDIL if it contains added sugar; pure juices exempt. For guidance only, not medical advice.